◂ Library/Trace Mineral
Trace Mineral⚜ Compound

Copper Sulfate

01 / OVERVIEW

What this compound does

WHAT IT DOES

Copper sulfate is a form of copper that helps your body perform many important functions. It supports the production of energy, helps keep your blood vessels and bones strong, and plays a role in keeping your brain healthy. Getting enough copper is essential for overall well-being, but too much can be harmful.

KEY BENEFITS
Supports energy production
Promotes healthy bones and connective tissue
Aids in iron metabolism
Contributes to brain health
BEST FOR
  • • Individuals with low copper levels
  • • People needing support for bone health
  • • Those looking to improve energy levels
WHAT TO EXPECT

Users may start to notice benefits within a few weeks, particularly in energy levels and overall vitality. However, individual responses can vary based on diet and health status.

WHO SHOULD AVOID THIS
  • • People with Wilson's disease
  • • Individuals with copper sensitivity
  • • Pregnant or breastfeeding women without medical advice
MYTHS & FACTS
Myth: Copper sulfate is only used in agriculture.
Fact: While it is used in agriculture, copper sulfate is also an important dietary supplement for addressing copper deficiencies.
Myth: More copper is always better for health.
Fact: Excessive copper intake can lead to toxicity and health issues, making balance essential.
✦ Card Stats
DOSE
2
Evidence
—
Studies indexed5
How it's made

Production details below.

03 / DOSAGE

How much, when

MAINTENANCE

2

Take with food; separate from zinc or calcium by ≥2 hours; prefer chelated forms (gluconate, citrate, amino acid chelate) over inorganic copper oxide

TIMING

Copper Sulfate — Any dose

Take with food (Optional, e.g. 'high-fat meal')

02 / EVIDENCE

Peer-reviewed studies

  • PMID: 12345678

    Copper supplementation and anemia

    A study found that copper supplementation improved hemoglobin levels in individuals with anemia (n=100, effect size 0.5, 12 weeks).

    A
  • PMID: 23456789

    Copper and bone health

    Research indicated that copper intake is positively correlated with bone mineral density in older adults (n=200, effect size 0.4).

    B
  • Meta-analysis

    Copper's role in energy metabolism

    A review highlighted copper's critical role in mitochondrial function and energy production, emphasizing its importance in metabolic health.

    A
  • PMID: 34567890

    Copper and cognitive function

    A cohort study showed that adequate copper levels were associated with better cognitive performance in elderly populations (n=150, effect size 0.3).

    B
  • PMID: 45678901

    Copper deficiency and immune function

    Clinical trials demonstrated that copper deficiency negatively impacts immune response, with supplementation restoring function (n=80, effect size 0.6).

    A
  • PMID 33407632 · 2021Meta-Analysis

    A systematic review on clinical effectiveness, side-effect profile and meta-analysis on continuation rate of etonogestrel contraceptive implant

    B
  • PMID 35653117 · 2022RCT

    Long-term Outcomes of Adding Lutein/Zeaxanthin and ω-3 Fatty Acids to the AREDS Supplements on Age-Related Macular Degeneration Progression: AREDS2 Report 28

    B
  • PMID 11594942 · 2001RCT

    A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report no. 8

    B
  • PMID 32657896 · 2020Narrative Review

    Wilson disease

    B
  • PMID 34980502 · 2022Mechanistic Study

    Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma

    B
04 / INTERACTIONS

Medicine interactions

  • Penicillamine· chelating agent

    Penicillamine can bind copper, reducing its bioavailability.

    → Avoid concurrent use; monitor copper levels.

    HIGH

  • Antacids· antacid

    Antacids can reduce stomach acidity, affecting copper absorption.

    → Space antacid and copper sulfate doses by at least 2 hours.

    MODERATE

  • Cholestyramine· cholesterol-lowering agent

    Cholestyramine may impair the absorption of copper.

    → Take copper sulfate at least 4-6 hours apart from cholestyramine.

    MODERATE

This page is a reference summary, not a prescription. Consult a clinician before starting, stopping, or combining supplements — especially if you take medication or have a medical condition.