About

A reference work, not a retailer.

Stack Lab indexes peer-reviewed research on commonly-taken supplements. Every claim links to the underlying study and carries an evidence grade. There are no affiliate links, no product rankings, and no sponsored content.

We write at three reading levels — plain, balanced, and technical — so a curious beginner and a practitioner can use the same page. The underlying data is identical; the language changes.

Routines are scheduled using pharmacokinetic rules: absorption pathways, food-status requirements, interaction severities, and known synergies. When two compounds compete for the same transporter, the schedule spaces them automatically.

None of this is medical advice. Speak with a clinician before starting, stopping, or combining supplements — especially if you take medication.

01Editorial standards

Evidence grades. A requires multiple high-quality RCTs or a recent meta-analysis. B requires RCTs with mixed findings or a single high-quality trial. C is for preclinical or observational evidence only.

Safety grades follow the same scale but reflect adverse event rates at typical doses in healthy adults.

Interactions are flagged at three severities. High means space the dose or speak with your doctor. Moderate means be aware. Low is for completeness.

02Scheduling engine

The routine builder uses a deterministic scheduling engine. Each supplement has rules for preferred timing (morning / midday / evening / bedtime), food requirements, fat solubility, stimulant and sedating properties.

When two supplements share a conflict — competing for the same mineral transporter, for instance — the engine moves one to a different dosing window and explains why. No guessing, no heuristics that silently fail.