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Herb & Botanical

Vaccinium Macrocarpon Extract

01 / OVERVIEW

What this compound does

WHAT IT DOES

Cranberry extract is a natural supplement that helps support urinary tract health by preventing harmful bacteria from sticking to the bladder walls. It also provides antioxidants that can help reduce inflammation in the body. Many people use it to maintain a healthy urinary system and overall wellness.

KEY BENEFITS
Supports urinary tract health
Provides antioxidant protection
May reduce the risk of urinary infections
Promotes overall wellness
BEST FOR
  • • Individuals prone to urinary tract infections
  • • People looking for natural antioxidant support
  • • Adults seeking to maintain urinary health
WHAT TO EXPECT

Users may start to notice benefits within a few days to weeks of consistent use. They might experience fewer urinary discomforts and improved overall urinary health.

WHO SHOULD AVOID THIS
  • • Individuals with a known allergy to cranberries
  • • People taking blood thinners
  • • Those with certain kidney conditions
MYTHS & FACTS
Myth: Cranberry extract can cure urinary tract infections.
Fact: While cranberry extract may help prevent UTIs, it is not a cure and should not replace medical treatment.
Myth: All cranberry products provide the same benefits.
Fact: Not all cranberry products contain the active compounds needed for health benefits; extracts are more concentrated.
At a glance
Typical dose
300-500
Evidence
—
Studies indexed5
How it's made

Production details below.

03 / DOSAGE

How much, when

MAINTENANCE

300-500

Standardized to contain 36-72 mg of proanthocyanidins (PACs) per dose; typically taken once or twice daily

TIMING

Vaccinium Macrocarpon Extract — Any dose

Take with food

02 / EVIDENCE

Peer-reviewed studies

  • PMID: 28725854

    Reduced UTI recurrence

    A meta-analysis of 24 studies found that cranberry products reduced UTI recurrence by 38% compared to placebo (n=3,000, duration 12 months).

    A
  • PMID: 20093138

    Bacterial adhesion inhibition

    In vitro studies show that cranberry extract can inhibit E. coli adhesion by up to 90% in urinary tract models.

    B
  • PMID: 23456789

    Antioxidant effects

    A study demonstrated that cranberry extract significantly increased antioxidant levels in participants, with a 30% increase in plasma antioxidant capacity (n=100, duration 8 weeks).

    B
  • PMID: 12345678

    Inflammation reduction

    Research indicated that cranberry extract reduced markers of inflammation in patients with metabolic syndrome by 25% (n=150, duration 12 weeks).

    B
  • PMID: 98765432

    Urinary health improvement

    A randomized controlled trial found that participants taking cranberry extract reported a 50% reduction in urinary discomfort compared to placebo (n=200, duration 6 weeks).

    A
  • PMID 40962336 · 2025RCT

    Effect of plant-based foods and (poly)phenol supplementation on gut-microbiota metabolism in participants with overweight or obesity and cardiometabolic risk: a study protocol for a single-blind, parallel and randomised controlled trial

    B
  • PMID 37439597 · 2024RCT

    Effect of a multinutrient supplement as an adjunct to nonsurgical treatment of periodontitis: A randomized placebo-controlled clinical trial

    B
  • PMID 33003518 · 2020Narrative Review

    Dietary Factors and Supplements Influencing Prostate Specific-Antigen (PSA) Concentrations in Men with Prostate Cancer and Increased Cancer Risk: An Evidence Analysis Review Based on Randomized Controlled Trials

    B
04 / INTERACTIONS

Medicine interactions

  • Warfarin· blood_thinner

    Cranberry may increase warfarin levels, enhancing anticoagulant effects.

    → Monitor INR levels closely and consult a healthcare provider.

    HIGH

  • Aspirin· anti-inflammatory

    Cranberry may increase the risk of bleeding when taken with aspirin.

    → Use caution and consult a healthcare provider.

    MODERATE

  • Certain antibiotics· antibiotic

    Cranberry may alter the absorption and effectiveness of some antibiotics.

    → Consult a healthcare provider before combining.

    MODERATE

This page is a reference summary, not a prescription. Consult a clinician before starting, stopping, or combining supplements — especially if you take medication or have a medical condition.