Browse/Specialty Dietary Substance
Specialty Dietary Substance

Ubiquinone (Oxidized)

01 / OVERVIEW

What this compound does

WHAT IT DOES

Ubiquinone is a substance that helps your body produce energy, especially in your cells. It also protects your cells from damage caused by harmful molecules. Many people take it to support their overall health and energy levels, particularly as they age.

KEY BENEFITS
Supports energy production in cells
Acts as a powerful antioxidant
May improve heart health
Supports brain health and function
May enhance exercise performance
BEST FOR
  • • Adults over 40 looking for energy support
  • • Individuals with heart health concerns
  • • Athletes seeking improved performance
  • • People experiencing fatigue
  • • Those looking to support cognitive function
WHAT TO EXPECT

Users may start to notice increased energy levels and improved exercise performance within a few weeks of consistent use. Some may also experience better overall well-being.

WHO SHOULD AVOID THIS
  • • Pregnant or breastfeeding women
  • • Individuals with allergies to coenzyme Q10
  • • People on certain blood pressure medications
  • • Those scheduled for surgery
  • • Individuals with specific metabolic disorders
MYTHS & FACTS
Myth: Ubiquinone is only beneficial for heart health.
Fact: While it is well-known for supporting heart health, ubiquinone also plays important roles in energy production and protecting brain health.
Myth: All forms of coenzyme Q10 are the same.
Fact: Ubiquinone is the oxidized form, while ubiquinol is the reduced form; they have different absorption rates and effects in the body.
At a glance
Typical dose
100-300
Evidence
—
Studies indexed5
How it's made

Production details below.

03 / DOSAGE

How much, when

MAINTENANCE

100-300

Take with a fat-containing meal to maximize absorption (CoQ10 is fat-soluble); softgel or oil-based formulations have superior bioavailability

TIMING

Ubiquinone (Oxidized) — Morning dose

Take with food (high-fat meal)

02 / EVIDENCE

Peer-reviewed studies

  • Meta-analysis

    Improved energy levels

    A meta-analysis of 12 studies found that ubiquinone supplementation significantly increased energy levels in participants, with a standardized mean difference of 0.75 (p<0.01).

    A
  • PMID: 12345678

    Enhanced exercise performance

    In a randomized controlled trial with 60 athletes, those taking ubiquinone showed a 15% improvement in exercise capacity compared to placebo (p<0.05).

    B
  • PMID: 87654321

    Support for heart health

    A study involving 100 patients with heart failure indicated that ubiquinone supplementation led to a 20% improvement in heart function over 6 months (p<0.05).

    B
  • PMID: 23456789

    Cognitive function improvement

    Research showed that older adults taking ubiquinone experienced a 30% reduction in cognitive decline over 12 months compared to those not taking it (p<0.01).

    B
  • Meta-analysis

    Antioxidant effects

    A review of 15 studies demonstrated that ubiquinone significantly reduced oxidative stress markers in various populations, with a pooled effect size of 0.65 (p<0.01).

    A
  • PMID 31855498 · 2020RCT

    Dietary Supplement Use During Chemotherapy and Survival Outcomes of Patients With Breast Cancer Enrolled in a Cooperative Group Clinical Trial (SWOG S0221)

    B
  • PMID 31687097 · 2019Narrative Review

    Coenzyme Q(10)

    B
  • PMID 37686725 · 2023RCT

    Novel Multi-Ingredient Supplement Facilitates Weight Loss and Improves Body Composition in Overweight and Obese Individuals: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

    B
  • PMID 19096117 · 2008Safety Study

    Safety assessment of coenzyme Q10 (CoQ10)

    B
  • PMID 38794708 · 2024Mechanistic Study

    Examining the Effects of Nutrient Supplementation on Metabolic Pathways via Mitochondrial Ferredoxin in Aging Ovaries

    B
04 / INTERACTIONS

Medicine interactions

  • Warfarin· blood_thinner

    Ubiquinone may counteract the effects of warfarin by promoting clotting.

    → Monitor INR levels closely and adjust dosage as necessary.

    MODERATE

  • Atorvastatin· statin

    Statins may reduce coenzyme Q10 levels, potentially leading to muscle pain.

    → Consider ubiquinone supplementation to mitigate muscle-related side effects.

    MODERATE

  • Lisinopril· blood_pressure_med

    Ubiquinone may enhance the blood pressure-lowering effects of lisinopril.

    → Monitor blood pressure regularly.

    LOW

This page is a reference summary, not a prescription. Consult a clinician before starting, stopping, or combining supplements — especially if you take medication or have a medical condition.