Browse/Longevity
Longevity

Trans-Resveratrol

01 / OVERVIEW

What this compound does

WHAT IT DOES

Trans-resveratrol is a natural compound found in certain plants that may help your body fight off stress and improve how your cells use energy. Some studies suggest it could support heart health and keep your brain sharp as you age. While research is ongoing, many people are interested in its potential to promote a longer, healthier life.

KEY BENEFITS
Supports heart health
May enhance brain function
Promotes healthy aging
Improves metabolic health
May reduce inflammation
BEST FOR
  • • Adults looking to support heart health
  • • Individuals interested in healthy aging
  • • People wanting to improve energy levels
  • • Those concerned about inflammation
  • • Fitness enthusiasts seeking recovery support
WHAT TO EXPECT

Users may start to notice benefits within a few weeks, such as improved energy levels and better overall well-being. However, individual responses can vary widely.

WHO SHOULD AVOID THIS
  • • Pregnant or breastfeeding women
  • • Individuals with hormone-sensitive conditions
  • • People taking blood thinners
  • • Those with known allergies to grapes
  • • Individuals on certain medications
MYTHS & FACTS
Myth: Trans-resveratrol is a miracle cure for aging.
Fact: While it shows promise in some studies, there is no definitive evidence that it can reverse aging or significantly extend lifespan.
Myth: All forms of resveratrol are equally effective.
Fact: Trans-resveratrol is the most studied form, and other forms may not have the same benefits or bioavailability.
At a glance
Typical dose
150-500 mg/day
Evidence
—
Studies indexed2
How it's made

Production details below.

03 / DOSAGE

How much, when

MAINTENANCE

150-500 mg/day

with food for absorption

TIMING

Trans-Resveratrol — Morning dose

Take with food for fat-soluble absorption

02 / EVIDENCE

Peer-reviewed studies

  • PMID: 17086194

    SIRT1 / longevity pathways

    Activates sirtuin pathways in vitro and in some animal models; human data limited.

    B
  • PMID: 22852062

    Cardiovascular markers

    Modest improvements in endothelial function in some trials.

    B
  • PMID 38794742 · 2024RCT

    Effects of Mediterranean Diet, Curcumin, and Resveratrol on Mild-to-Moderate Active Ulcerative Colitis: A Multicenter Randomized Clinical Trial

    B
  • PMID 39519608 · 2024RCT

    The Administration of Resveratrol and Vitamin C Reduces Oxidative Stress in Postmenopausal Women-A Pilot Randomized Clinical Trial

    B
  • PMID 25652123 · 2015Pharmacokinetic Study

    The pharmacology of resveratrol in animals and humans

    B
  • PMID 32023928 · 2020Narrative Review

    Nutraceuticals and Hypertensive Disorders in Pregnancy: The Available Clinical Evidence

    B
  • PMID 29289576 · 2018Narrative Review

    Botanicals and phytochemicals active on cognitive decline: The clinical evidence

    B
04 / INTERACTIONS

Medicine interactions

  • Warfarin· blood_thinner

    Trans-resveratrol may enhance the effects of blood thinners, increasing bleeding risk.

    → Monitor INR closely and consult a healthcare provider.

    HIGH

  • SSRIs· SSRI

    May affect serotonin levels, leading to potential interactions.

    → Consult a healthcare provider before combining.

    MODERATE

  • Antihypertensives· blood_pressure_med

    May enhance blood pressure-lowering effects.

    → Monitor blood pressure regularly.

    MODERATE

This page is a reference summary, not a prescription. Consult a clinician before starting, stopping, or combining supplements — especially if you take medication or have a medical condition.