Tesamorelin
What this compound does
Tesamorelin is an FDA-approved peptide that lowers deep belly fat by boosting your own growth hormone. It has real human trial evidence.
- • Patients with HIV-associated visceral fat (approved use)
- • Researchers studying GHRH analogs
Daily subcutaneous injection; visceral-fat changes appear over weeks to months.
- • People with active cancer
- • Pregnant people (contraindicated)
- • Uncontrolled diabetics without supervision
Manufactured to pharmacopeial standards, lyophilised for reconstitution.
How much, when
Peer-reviewed studies
- PMID: 17986662A
Reduces visceral adipose tissue
Phase 3 trials showed tesamorelin significantly reduced visceral fat vs placebo in HIV lipodystrophy.
- PMID: 20554975A
Raises IGF-1
Increases IGF-1 in a dose-dependent, reversible manner.
- PMID 17986662 · 2007rctA
Tesamorelin for visceral fat in HIV lipodystrophy (Phase 3)
Reduced visceral fat
- PMID 20554975 · 2010rctA
Effects of tesamorelin on IGF-1 and safety
Dose-dependent IGF-1 rise
Medicine interactions
- MODERATE
Insulin / antidiabetics· antidiabetic
GH-mediated insulin resistance may raise glucose.
→ Monitor glucose; dose adjustments may be needed.
- MODERATE
Corticosteroids· steroid
Blunt GH response.
→ Efficacy may be reduced.
This page is a reference summary, not a prescription. Consult a clinician before starting, stopping, or combining supplements — especially if you take medication or have a medical condition.