Browse/Peptide
Peptide

Tesamorelin

01 / OVERVIEW

What this compound does

WHAT IT DOES

Tesamorelin is an FDA-approved peptide that lowers deep belly fat by boosting your own growth hormone. It has real human trial evidence.

KEY BENEFITS
Proven visceral-fat reduction
FDA-approved (for HIV lipodystrophy)
Reversible IGF-1 elevation
BEST FOR
  • Patients with HIV-associated visceral fat (approved use)
  • Researchers studying GHRH analogs
WHAT TO EXPECT

Daily subcutaneous injection; visceral-fat changes appear over weeks to months.

WHO SHOULD AVOID THIS
  • People with active cancer
  • Pregnant people (contraindicated)
  • Uncontrolled diabetics without supervision
MYTHS & FACTS
Myth:
Fact:
At a glance
Typical dose
2 mg subcutaneously once daily (approved dose)
Evidence
Studies indexed2
How it's made

Manufactured to pharmacopeial standards, lyophilised for reconstitution.

03 / DOSAGE

How much, when

MAINTENANCE

2 mg subcutaneously once daily (approved dose)

fixed 2 mg daily

TIMING

Tesamorelin — Bedtime dose

Standard dosing.

02 / EVIDENCE

Peer-reviewed studies

  • PMID: 17986662

    Reduces visceral adipose tissue

    Phase 3 trials showed tesamorelin significantly reduced visceral fat vs placebo in HIV lipodystrophy.

    A
  • PMID: 20554975

    Raises IGF-1

    Increases IGF-1 in a dose-dependent, reversible manner.

    A
  • PMID 17986662 · 2007rct

    Tesamorelin for visceral fat in HIV lipodystrophy (Phase 3)

    Reduced visceral fat

    A
  • PMID 20554975 · 2010rct

    Effects of tesamorelin on IGF-1 and safety

    Dose-dependent IGF-1 rise

    A
04 / INTERACTIONS

Medicine interactions

  • Insulin / antidiabetics· antidiabetic

    GH-mediated insulin resistance may raise glucose.

    Monitor glucose; dose adjustments may be needed.

    MODERATE
  • Corticosteroids· steroid

    Blunt GH response.

    Efficacy may be reduced.

    MODERATE

This page is a reference summary, not a prescription. Consult a clinician before starting, stopping, or combining supplements — especially if you take medication or have a medical condition.