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Peptide

TB-500 (Thymosin Beta-4)

01 / OVERVIEW

What this compound does

WHAT IT DOES

TB-500 is a lab version of a natural peptide that helps cells move and repair. Athletes use it for recovery, but human proof is thin.

KEY BENEFITS
May aid soft-tissue recovery and flexibility (animal data)
Studied for wound and cardiac repair
BEST FOR
  • • Athletes exploring recovery peptides
WHAT TO EXPECT

Not FDA-approved; sold as a research chemical. Human benefits are anecdotal.

WHO SHOULD AVOID THIS
  • • People with active cancer
  • • Pregnant or breastfeeding people
  • • Those wanting proven, approved therapies
MYTHS & FACTS
Myth:
Fact:
Myth:
Fact:
At a glance
Typical dose
2 mg/week maintenance (research protocols)
Loading: 2-2.5 mg 2x/week for 4-6 weeks (research protocols)
Evidence
—
Studies indexed2
How it's made

Chemically synthesised peptide, HPLC-purified, lyophilised.

03 / DOSAGE

How much, when

MAINTENANCE

2 mg/week maintenance (research protocols)

LOADING PROTOCOL

2-2.5 mg 2x/week for 4-6 weeks (research protocols)

subcutaneous

TIMING

TB-500 (Thymosin Beta-4) — Morning dose

Take on empty stomach

02 / EVIDENCE

Peer-reviewed studies

  • PMID: 22101380

    Actin regulation and cell migration

    Thymosin beta-4 sequesters G-actin and promotes cell migration central to wound repair.

    B
  • PMID: 15229603

    Cardiac repair (preclinical)

    Animal models show improved cardiomyocyte survival and vascular growth after injury.

    C
  • PMID 22101380 · 2011review

    Thymosin beta-4: actin sequestration and tissue repair

    Mechanistic support

    B
04 / INTERACTIONS

Medicine interactions

  • No documented drug interactions

    No human interaction data.

    → Disclose to your clinician; avoid if you have active malignancy pending oncologist input.

    LOW

This page is a reference summary, not a prescription. Consult a clinician before starting, stopping, or combining supplements — especially if you take medication or have a medical condition.