◂ Library/Amino Acid Derivative
Amino Acid Derivative⚜ Compound

Phosphatidylserine

01 / OVERVIEW

What this compound does

WHAT IT DOES

Phosphatidylserine is a substance that helps your brain work better and stay healthy. It supports memory and thinking skills, especially as we age. Some people take it to help with stress and improve their focus throughout the day.

KEY BENEFITS
Supports memory and learning
May reduce stress levels
Improves focus and attention
Promotes brain health as you age
BEST FOR
  • • Older adults looking to maintain cognitive function
  • • Students needing better focus during studies
  • • Individuals experiencing high stress
WHAT TO EXPECT

Users may start to notice improvements in focus and memory within a few weeks of consistent use. Effects can vary, and some may experience benefits sooner.

WHO SHOULD AVOID THIS
  • • Pregnant or breastfeeding women
  • • Individuals with soy allergies
  • • Those on blood-thinning medications without consulting a doctor
MYTHS & FACTS
Myth: Phosphatidylserine is only for older adults.
Fact: While it is often marketed for cognitive health in older adults, younger individuals can also benefit from its effects on focus and stress management.
Myth: All phosphatidylserine supplements are the same.
Fact: Quality can vary significantly between products, with some derived from soy and others from cabbage, affecting their efficacy and suitability for different individuals.
✦ Card Stats
DOSE
100-400 mg/day
Evidence
—
Studies indexed2
How it's made

Production details below.

03 / DOSAGE

How much, when

MAINTENANCE

100-400 mg/day

split 3x with meals; last dose before 5pm

TIMING

Phosphatidylserine — Morning dose

Take with food for fat-soluble absorption

02 / EVIDENCE

Peer-reviewed studies

  • PMID: 2021880

    Cognitive function in aging

    Phosphatidylserine improved memory and cognitive function in elderly with memory complaints.

    B
  • PMID: 18981063

    Cortisol response to exercise

    Blunted cortisol rise after intense exercise in some trials.

    B
  • PMID 40908273 · 2026Narrative Review

    Pharmacological and Mechanistic Interventions for Cognitive Impairment Associated With Schizophrenia: A Review of Registered Clinical Trials

    B
  • PMID 28375181 · 2017Narrative Review

    Dietary Metabolites and Chronic Kidney Disease

    B
  • PMID 31677711 · 2019RCT

    Soy isoflavones and cholecalciferol reduce inflammation, and gut permeability, without any effect on antioxidant capacity in irritable bowel syndrome: A randomized clinical trial

    B
  • PMID 29860335 · 2018RCT

    Metabolic Effects of Betaine: A Randomized Clinical Trial of Betaine Supplementation in Prediabetes

    B
  • PMID 23709455 · 2013Pharmacokinetic Study

    A pilot study on the serum pharmacokinetics of nattokinase in humans following a single, oral, daily dose

    B
04 / INTERACTIONS

Medicine interactions

  • Warfarin· blood_thinner

    Phosphatidylserine may enhance the effects of blood thinners, increasing bleeding risk.

    → Consult a healthcare provider before use.

    HIGH

  • SSRIs· SSRI

    May influence serotonin levels, potentially leading to increased side effects.

    → Monitor for increased side effects if taken together.

    MODERATE

  • Antidepressants· antidepressant

    Could affect neurotransmitter balance, leading to unexpected effects.

    → Consult a healthcare provider for guidance.

    MODERATE

This page is a reference summary, not a prescription. Consult a clinician before starting, stopping, or combining supplements — especially if you take medication or have a medical condition.