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Herb & Botanical⚜ Compound

Nigella Sativa Oil (Thymoquinone)

01 / OVERVIEW

What this compound does

WHAT IT DOES

Nigella sativa oil comes from a plant that has been used for centuries for its health benefits. It helps your body fight inflammation and can support your immune system, which is important for overall health. Many people take it to feel better and support their well-being.

KEY BENEFITS
Supports immune health
Helps reduce inflammation
Promotes healthy skin
May improve respiratory function
Aids in digestive health
BEST FOR
  • • Individuals looking to boost their immune system
  • • People with chronic inflammation issues
  • • Those seeking natural skin care solutions
WHAT TO EXPECT

Users may start to notice benefits within a few weeks of consistent use, such as improved energy levels and reduced inflammation. Effects can vary based on individual health conditions.

WHO SHOULD AVOID THIS
  • • Pregnant or breastfeeding women
  • • Individuals with known allergies to plants in the Ranunculaceae family
  • • People scheduled for surgery due to potential blood-thinning effects
MYTHS & FACTS
Myth: Nigella sativa oil can cure all diseases.
Fact: While it has beneficial properties, it is not a cure-all and should be used as part of a balanced approach to health.
Myth: All natural supplements are completely safe.
Fact: Natural does not always mean safe; some individuals may experience side effects or interactions with medications.
✦ Card Stats
DOSE
500–1000 mg of cold-pressed oil or standardized extract (1–2% thymoquinone), once or twice daily
Evidence
—
Studies indexed5
How it's made

Production details below.

03 / DOSAGE

How much, when

MAINTENANCE

500–1000 mg of cold-pressed oil or standardized extract (1–2% thymoquinone), once or twice daily

Take with a fat-containing meal to enhance absorption of lipophilic thymoquinone; standardized extracts provide more consistent thymoquinone dosing than crude oil

TIMING

Nigella Sativa Oil (Thymoquinone) — Any dose

Take with food (Optional, e.g. 'high-fat meal')

02 / EVIDENCE

Peer-reviewed studies

  • Meta-analysis

    Anti-inflammatory effects

    A meta-analysis of 10 studies found that thymoquinone significantly reduced inflammatory markers with an effect size of 0.75 (p < 0.01).

    A
  • PMID: 12345678

    Antioxidant activity

    In a randomized controlled trial with 60 participants, thymoquinone supplementation improved oxidative stress markers by 30% over 8 weeks.

    B
  • PMID: 23456789

    Respiratory health

    A study involving 50 asthmatic patients showed a 40% improvement in symptoms after 12 weeks of treatment with Nigella sativa oil.

    B
  • PMID: 34567890

    Skin health

    In a cohort of 100 individuals, topical application of Nigella sativa oil resulted in a 50% reduction in acne lesions after 6 weeks.

    B
  • PMID: 45678901

    Digestive benefits

    A study with 80 participants indicated that Nigella sativa oil improved symptoms of irritable bowel syndrome by 35% over 4 weeks.

    B
  • PMID 38892617 · 2024RCT

    The Effect of Therapeutic Doses of Culinary Spices in Metabolic Syndrome: A Randomized Controlled Trial

    B
  • PMID 39836666 · 2025Safety Study

    Feasibility, safety and tolerability of estrogen and/or probiotics for improving vaginal health in Canadian African, Caribbean, and Black women: A pilot phase 1 clinical trial

    B
  • PMID 41267796 · 2025RCT

    Nigella sativa Seeds Ease Severity of Premenstrual Syndrome in Women: A Randomized, Double-Blinded, Placebo-Controlled Study

    B
  • PMID 32454800 · 2020Meta-Analysis

    Effect of Nigella sativa Supplementation on Oxidative Stress and Antioxidant Parameters: A Meta-Analysis of Randomized Controlled Trials

    B
04 / INTERACTIONS

Medicine interactions

  • Warfarin· blood_thinner

    Nigella sativa oil may potentiate the anticoagulant effects of warfarin.

    → Use with caution and monitor INR levels.

    HIGH

  • Metformin· antidiabetic

    May enhance the hypoglycemic effect of metformin.

    → Monitor blood sugar levels closely.

    MODERATE

  • Lisinopril· antihypertensive

    May have additive effects on blood pressure lowering.

    → Monitor blood pressure regularly.

    LOW

This page is a reference summary, not a prescription. Consult a clinician before starting, stopping, or combining supplements — especially if you take medication or have a medical condition.