Nicotinamide Mononucleotide (NMN)
What this compound does
Nicotinamide Mononucleotide, or NMN, is a substance that helps your body produce energy more efficiently. It supports your cells in functioning well, which can lead to better overall health and vitality. Some people take it to feel more energetic and to support their brain health as they age.
- • Adults looking to boost energy
- • Individuals concerned about aging
- • People wanting to support cognitive health
Users may start to notice increased energy and improved focus within a few weeks of consistent use. Effects can vary based on individual health and lifestyle.
- • Pregnant or breastfeeding women
- • Individuals with severe allergies to supplements
- • People taking certain medications without consulting a doctor
Production details below.
How much, when
Peer-reviewed studies
- PMID: 33888596B
NAD+ elevation
Oral NMN significantly increased blood NAD+ levels in healthy adults.
- PMID: 33888596B
Insulin sensitivity
NMN supplementation improved muscle insulin sensitivity in postmenopausal women.
- PMID 37478182 · 2023Narrative ReviewB
What is really known about the effects of nicotinamide riboside supplementation in humans
- PMID 35235774 · 2022RCTB
The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson's disease
- PMID 27721479 · 2016Clinical StudyB
Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
- PMID 31278280 · 2019Safety StudyB
Safety and Metabolism of Long-term Administration of NIAGEN (Nicotinamide Riboside Chloride) in a Randomized, Double-Blind, Placebo-controlled Clinical Trial of Healthy Overweight Adults
- PMID 32383227 · 2021Mechanistic StudyB
Possible mechanisms of cancer prevention by nicotinamide
Medicine interactions
- MODERATE
Blood thinners· blood_thinner
NMN may enhance the effects of blood thinners, increasing the risk of bleeding.
→ Consult a healthcare provider before use.
- LOW
Antidepressants· SSRI
NMN may affect serotonin levels, potentially altering the effects of SSRIs.
→ Monitor for changes in mood and consult a healthcare provider.
- LOW
Statins· statin
NMN may influence lipid metabolism, which could affect statin efficacy.
→ Consult with a healthcare provider for personalized advice.
This page is a reference summary, not a prescription. Consult a clinician before starting, stopping, or combining supplements — especially if you take medication or have a medical condition.