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Nootropics⚜ Compound

Lion's Mane Mushroom

01 / OVERVIEW

What this compound does

WHAT IT DOES

Lion's Mane Mushroom is a natural supplement that may help support brain health and improve memory. It is thought to encourage the growth of new brain cells and protect existing ones, which can be beneficial for overall cognitive function. Many people take it to help with focus and mental clarity, especially as they age.

KEY BENEFITS
Supports cognitive function
May enhance memory
Promotes nerve health
Aids in mental clarity
May reduce mild anxiety
BEST FOR
  • • Individuals looking to improve memory
  • • Older adults wanting to support brain health
  • • Students needing better focus during studies
WHAT TO EXPECT

Users may start to notice improvements in focus and memory within a few weeks of consistent use. Some may also experience a calming effect on mood.

WHO SHOULD AVOID THIS
  • • People with mushroom allergies
  • • Individuals on immunosuppressive therapy
  • • Pregnant or breastfeeding women
MYTHS & FACTS
Myth: Lion's Mane Mushroom can cure Alzheimer's disease.
Fact: While some studies suggest potential cognitive benefits, there is currently no cure for Alzheimer's disease, and more research is needed to establish efficacy.
Myth: All mushrooms are safe and beneficial.
Fact: Not all mushrooms are safe; some can be toxic. Lion's Mane should be sourced from reputable suppliers to ensure safety.
✦ Card Stats
DOSE
500-1000 mg/day (fruiting body extract)
Evidence
—
Studies indexed2
How it's made

Production details below.

Options to buy

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03 / DOSAGE

How much, when

MAINTENANCE

500-1000 mg/day (fruiting body extract)

look for >25% beta-glucans

TIMING

Lion's Mane Mushroom — Morning dose

Take with food (meal)

02 / EVIDENCE

Peer-reviewed studies

  • PMID: 19001767

    Cognitive function

    RCT in mild cognitive impairment showed improved cognitive scores with 250 mg 3x/day over 16 weeks.

    B
  • PMID: 18844328

    Nerve growth factor stimulation

    Erinacines cross the blood-brain barrier and stimulate NGF synthesis in preclinical models.

    B
  • PMID 23440782 · 2013In vitro/In vivo

    Hericium erinaceus and Nerve Growth Factor Synthesis

    Hericenones and erinacines stimulated NGF synthesis in animal models.

    B
  • PMID 18844328 · 2008 · n=30RCT

    Lion's Mane and Cognitive Function in Mild Cognitive Impairment

    Significant improvement on cognitive function scales vs placebo after 16 weeks.

    B
  • PMID 20834180 · 2010 · n=30RCT

    Reduction of Depression and Anxiety by Hericium erinaceus

    Four weeks of intake reduced depression and anxiety scores in menopausal women.

    B
04 / INTERACTIONS

Medicine interactions

  • Warfarin· blood_thinner

    Potential to enhance anticoagulant effects, increasing bleeding risk.

    → Monitor INR levels closely if used together.

    MODERATE

  • Immunosuppressants· immunosuppressive

    Potential to stimulate immune response, counteracting medication effects.

    → Use with caution and under medical supervision.

    MODERATE

  • SSRIs· SSRI

    May affect serotonin levels; caution advised.

    → Consult with a healthcare provider before combining.

    LOW

This page is a reference summary, not a prescription. Consult a clinician before starting, stopping, or combining supplements — especially if you take medication or have a medical condition.