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Peptide

Ipamorelin

01 / OVERVIEW

What this compound does

WHAT IT DOES

Ipamorelin nudges your body to release its own growth hormone in natural pulses, without the side effects of older drugs. Used for recovery and sleep.

KEY BENEFITS
Stimulates natural GH pulses
Minimal cortisol/prolactin bump
May support recovery and deep sleep
BEST FOR
  • • Adults exploring GH-axis support for recovery
  • • People who want a gentler secretagogue
WHAT TO EXPECT

Often stacked with a GHRH like CJC-1295. Not FDA-approved for anti-aging or performance use.

WHO SHOULD AVOID THIS
  • • People with active cancer
  • • Diabetics without medical supervision
  • • Pregnant or breastfeeding people
MYTHS & FACTS
Myth:
Fact:
Myth:
Fact:
At a glance
Typical dose
200-300 mcg 1-3x/day (research protocols)
Evidence
—
Studies indexed2
How it's made

Pentapeptide synthesised and HPLC-purified, lyophilised for reconstitution.

03 / DOSAGE

How much, when

MAINTENANCE

200-300 mcg 1-3x/day (research protocols)

subcutaneous, often pre-bed on empty stomach

TIMING

Ipamorelin — Bedtime dose

Take on empty stomach

02 / EVIDENCE

Peer-reviewed studies

  • PMID: 9849822

    Selective GH release

    Ipamorelin raises GH without meaningfully increasing cortisol or prolactin, unlike older secretagogues.

    B
  • PMID: 18048423

    Preserved GI motility signal

    Ghrelin-receptor agonism also influences gastric motility in studies.

    C
  • PMID 9849822 · 1998animal

    Ipamorelin, the first selective growth hormone secretagogue

    Selective GH release

    B
04 / INTERACTIONS

Medicine interactions

  • Insulin / antidiabetics· antidiabetic

    GH can raise blood glucose and reduce insulin sensitivity.

    → Monitor blood glucose; coordinate with your clinician.

    MODERATE

  • Corticosteroids· steroid

    May blunt GH response.

    → Be aware GH stimulation may be reduced.

    LOW

This page is a reference summary, not a prescription. Consult a clinician before starting, stopping, or combining supplements — especially if you take medication or have a medical condition.