GHK-Cu (Copper Peptide)
What this compound does
GHK-Cu is a copper-carrying peptide used in skincare to firm skin, smooth wrinkles, and help wounds heal. It is one of the more proven cosmetic peptides.
- • People wanting evidence-based anti-aging skincare
- • Topical hair-support routines
Used topically (serums) or in cosmetic injectables; visible skin changes over weeks.
- • People with copper allergy
- • Those layering many strong actives (irritation risk)
Glycyl-L-histidyl-L-lysine synthesised and complexed with copper(II); formulated into serums.
How much, when
Peer-reviewed studies
- PMID: 25382603B
Skin remodelling and collagen
GHK-Cu stimulates collagen, elastin, and glycosaminoglycan synthesis and improves skin appearance in controlled cosmetic studies.
- PMID: 25664619B
Wound healing
Promotes angiogenesis and tissue repair in wound-healing models.
- PMID 25382603 · 2015reviewB
GHK-Cu peptide in skin remodelling and anti-aging
Improved skin metrics
Medicine interactions
- LOW
Topical retinoids / acids· dermatologic
Combined actives can increase irritation.
→ Alternate application or space usage.
This page is a reference summary, not a prescription. Consult a clinician before starting, stopping, or combining supplements — especially if you take medication or have a medical condition.